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Abstract ABS-390

The Ruling of Novel Drugs to The Molecular Targets on Variant Pathologicalhis Henik Setiyaningsih 1, Imron Wahyu Hidayat1, Alfian Syarifuddin1, Setiyo Budi Santoso1, Ratna Wijayatri1a Corresponding Author: Henik Setiyaningsih Setiyaningsih

Question from Ms. Dhea Nur Hikmah 2022.12.21 14:47:38 What is the relationship between the biological gene IL6R as an antidepressant?

Reply from Ms. Henik Setiyaningsih Setiyaningsih 2022.12.21 14:49:00 Identified IL6R as the most promising target gene for depression according to clinical and preclinical evidence. IL6R was one of the target genes with the highest functional annotation score and was a highly promising target in the treatment of depression. IL6R regulates systemic inflammation, which is associated with depression development.

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