The Impact Of Heparin On Hemoglobin Levels During Blood Gas Analysis In Critical Patients Beti Kristinawati (a*), Fahrun Nur Rosyid (b), Muhammad Nur Hidayanto (c), Ardhu Rizkiawan (d), Nyofan Wahyu Mardana (e)
a,b: Medical-Surgical Nursing Department, Universitas Muhammadiyah Surakarta, 57162, Indonesia
*bk115[at]ums.ac.id
c,d: Graduate Professional Nursing Student, Universitas Muhammadiyah Surakarta, 57162, Indonesia
e: Professional Nursing Student, Universitas Muhammadiyah Surakarta, 57162, Indonesia
Abstract
Introduction: Laboratory anticoagulants are acidic, resulting in a fall in blood hydrogen potential (pH), an increase in plasma oxygen (PO2) levels, and a reduction in hemoglobin levels. This study intends to assess the difference in hemoglobin levels between blood gas analysis (BGA) examinations performed with sodium heparin and lithium heparin anticoagulants utilizing Ethylene Diamine Tetraacetic Acid (EDTA) anticoagulants.
Method: Analytical observational research was performed on sixty samples of hemoglobin concentration test findings on BGA examination of arterial patients who were not receiving anticoagulant medication.
Results: Statistical analysis obtained the results of differences in hemoglobin concentrations examined using anticoagulants sodium heparin with EDTA (p-value = 0.000). Hemoglobin concentrations examined using anticoagulants lithium heparin with EDTA (p-value 0.002).
Conclusions: There was a substantial difference in the assessment of hemoglobin concentration with sodium and lithium heparin anticoagulants and with EDTA anticoagulants. The final concentration of heparin-blood and dilution in the blood is the result of selecting anticoagulant kinds and quantities, thus it must be taken into account when collecting blood samples because it affects laboratory test findings.
