The Relation Between D-dimer Level and Chest X-Ray (CXR) Scoring in COVID-19 Patients, What we can learn from? Tersia Viradanti, Yudith Yunia Kusmala
Internal Medicine Department, Jenderal Achmad Yani University Faculty of Medicine, Cimahi, Indonesia
Abstract
Coronavirus disease is a kind of pneumonia cause by infection of SARS-CoV-2. In most cases, patients only get mild manifestation or even asymptomatic. Some patient can get severe disease, especially elderly people or someone with comorbid, leading to cytokines storm that triggers SIRS and induce coagulation dysregulation (marked by D-dimer elevation) so that increasing risk to get thrombosis. Recent pathology finding suggest that micro-thrombosis has contribution to ARDS due to lung^s fibrosis. We use a CXR scoring system to assess lung parenchyma involvement in COVID-19 patients and D-dimer level to see coagulopathy then performing an analysis to investigate the relationship between both. Based on the Spearman test, we find that there is a significant relationship between D-dimer level and CXR scores of COVID-19 patients describe as a positive correlation (p=0.023- r=0.358).
