The Correlation Between D-Dimer Level and Chest X-Ray Score in COVID-19 Patients Tersia Viradanti, Yudith Yunia Kusmala
1.Bachelor Degree of Medical Faculty of Universitas Jenderal Achmad Yani, Cimahi Indonesia
2.Internal Medicine Dept. Medical Faculty of Universitas Jenderal Achmad Yani,Cimahi Indonesia,Correspondency: yudith.yunia[at]lecture.unjani.ac.id
Abstract
ABSTRACT
Introduction: Coronavirus disease-2019 (COVID-19) is pneumonia caused by SARS-CoV-2. In severe cases, COVID-19 patients can get excessive inflammatory response resulting in cytokines storm that induce dysregulation on the coagulation cascade and make lung pathology worse. D-dimer levels in COVID-19 patients may rise due to pro-inflammatory cytokines produced by lung parenchymal involvement in infection. The degree of lung parenchymal involvement on COVID-19 infection can be measured semi-quantitatively with chest X-ray scoring. This study is held to investigating the relationship between D-dimer level and thoracic photo scoring in hospitalized COVID-19 patients at the isolation room of the Dustira Hospital and Kebon Jati.
Methods: It is a cross-sectional analytic design study with secondary data taken from the medical record of forty patients confirmed by COVID-19 that is hospitalized in Dustira and Kebon Jati Hospital during March - December 2020.
Results: The subject consisted of 23 females (57,5%) and 17 males (42,5%) with mostly aged between 40 - 59 years old. There is a significant relationship between D-dimer level and thoracic photo scoring value of COVID-19 patients hospitalized in Dustira Hospital and Kebon Jati Hospital marked by positive correlation from spearman test on both (p=0.023- r = 0.358). The correlation between elevating of D-dimer level and chest X-ray score is thought to be due to cytokine storm that causes increasing of the alveolar lesion and also microthrombus formation.
Conclusion: there is a correlation between D-dimer level and chest X-ray score in hospitalized COVID-19 patients at the isolation room of the Dustira Hospital and Kebon Jati.
