Purification of Flavonoid from Sonchus Arvensis (Linn.) Leaf Extract by Ultrafiltration Membrane Putu Teta Prihartini Aryanti, Gatra Buana Winiarti, Gina Shofi Pratiwi, Gatot Trilaksono, Suryani, and Novie Elvinawaty Mauliku
Universitas Jenderal Achmad Yani
Abstract
In recent years, the extraction of high-added value compounds, such as flavonoids, from a natural product has progressively been conducted by the food and pharmaceutical industries due to their high-value impact on human health. In this research, ultrafiltration (UF) membrane was used to purify flavonoid extract solution. The effect of membrane charge, polysulfone (PSf) concentration, and operating pressure were studied on the permeate flux and the separation efficiency of flavonoid compounds. The results showed that the sulfonated UF membrane produced a higher flux and separation efficiency than the non-sulfonated UF membrane, which were 263 L.m2.h and 160%, respectively. An increase in operating pressure will have a larger permeate flux, but it is prone to internal fouling, which results in a sharp decrease in flux during the 2 (two) hour ultrafiltration process. It is hoped that the tightly structured UF membrane can be an alternative process for the separation and purification of active compounds that can be carried out at room pressure and temperature.
Keywords: active compound, low energy, purification, tight structure, ultrafiltration