The effect of garlic extract (Allium sativum L) on the blood image of mice infected with Trypanosoma evansi Drh. Zainal Abidin Kholilullah, M.Kes- Drh. Adryani Ris, M.Si
Program studi Kedokteran Hewan
Fakultas Kedokteran
Universitas Hasanuddin
Abstract
ABSTRACT
One of the diseases that commonly attack livestock, especially horses and cattle is Surra disease. This disease is caused by infection with the parasite Trypanosoma evansi (T. evansi). In the animal^s body, T. evansi will enter the circulatory system and carry out breeding activities that result in damage to blood cells, especially red blood cells. Garlic (Allium sativum L) has been widely researched and the results are known to contain active compounds including flavonoids and Allicin (diallyl thiosulfinate). Allicin is one of the most biologically active components contained in garlic. This component, together with other sulfur components contained in garlic, has a role in giving garlic a distinctive odor. Allicin not only has antibacterial effects, but also anti- parasitic and antiviral effects (Londhe, 2011). Based on the Allicin content, we will test its activity on the blood image of mice as experimental animals
that have been infected with Trypanosoma evansi parasite and then will evaluate its effect on the image of the mice^s blood. It is hoped that this research can be a source of information for researchers and the public about the benefits of garlic in treating trypanosomiasis cases.