An Investigation of Biopsychosocial Risk Factors Among Taiwanese Women With A Family History of Breast Cancer
Sabiah Khairi1 and Min-Huey Chung1,2

1 School of Nursing, College of Nursing, Taipei Medical University, Taipei City 11031, Taiwan
2 Department of Nursing, Shuang Ho Hospital, Taipei Medical University, New Taipei City 23561, Taiwan

Abstract

Background: Identifying breast cancer risk factors is a critical component of preventive strategy for this disease. Women with family history of breast cancer (FHBC) in their first-degree relatives have an approximately two-fold higher risk than women without family history. However, the existing studies documenting biopsychosocial risk factors among healthy women with FHBC were limited.
Purpose: We aimed to explore the biopsychosocial risk factors associated with breast cancer development in Taiwanese women
Methods: The study population includes participants of the Taiwan Biobank from 2008 to 2018. A total of 3,214 healthy women aged range 30-75 years old were considered eligible for enrollment. Participants were divided into FHBC (1,830) and non-FHBC (1,384). A self-reporting technique is mainly used to acquire the risk factors related to breast cancer which include biological, psycho-behavioral, and social factors. The univariate and multiple logistic regression analyses were performed to identify the significant associated biopsychosocial factors. All the analyses were conducted using Statistical Package for Social Science (SPSS). This study has been approved by the Joint Institutional Review Board of Taipei Medical University (No. N201804027).
Results: In our study, most participants with FHBC were more than 45 years old (67.4%). Multiple logistic regression showed that the breast cancer risk was associated with age (OR, 2.56- 95% CI, 2.276-3.102, p: <0.001), a family has other cancer (OR, 1.51- 95% CI, 1.006-2.271 p: 0.047), and educational level (OR, 3.45- 95% CI, 2.781-4.279, p: <0.001) were significantly associated with the breast cancer development
Conclusion: The biopsychosocial factors including age &#8805- 45 years old, having family members who have other cancer, and educational level are more likely to increase the risk of breast cancer. These identified biopsychosocial factors can be considered for established evidence-based intervention to prevent the development of breast cancer, especially in the Taiwanese population with FHBC

Keywords: Biopsychosocial risk factors, family history of breast cancer

Topic: Prevention/Health Promotion