The potential of Cinnamomum cassia in lowering blood sugar levels in patients with type 2 diabetes mellitus
Dwi Wulandari Aaas Hamka (a*), Dhani Redhono (b). Ratih Puspita Febrinasari (b)

a. Clinical Nutrition Department Universitas Sebelas Maret, Jl. Sutami No.36, Surakarta, Indonesia
b. Department of Internal Medicine, Universitas Sebelas Maret and Moewardi General Hospital, Surakartan, Indonesia
b. Department of Pharmacology, Universitas Sebelas Maret, Surakartan, Indonesia

Abstract

Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia that occurs due to defects in insulin secretion, insulin action, or both. People with diabetes mellitus in the world at the age of 20-79 years reached 463 million people or 9.3% of the total population of the same age. The prevalence of diabetes mellitus is estimated to increase until in 2030 it will reach 578 million and in 2045 it is predicted to reach 700 million. Spices such as Cinnamomum cassia have been of interest due to their phytochemical composition that exerts hypoglycemic effects with the potential for the management of type 2 diabetes mellitus. the aim is to determine Cinnamomum cassia as an alternative treatment for patients with type 2 diabetes mellitus. The method is a systematic review of many journals. Cinnamon has several active ingredients, namely cinnamate, cinnamaldehyde, polyphenols, and flavonoids. cinnamaldehyde can increase glucose transport by GLUT 4 in adipose cells and skeletal muscle so that it can significantly reduce blood glucose.

Keywords: Cinnamomum cassia- Treatment- Type 2 diabetes mellitus

Topic: Medical : basic science, clinical, translational research, medical education, and miscellaneous