Transarterial Chemoembolization for Hepatocelullar Carcinoma
dr. Puspitasari Sandra Wijaya, dr. Hilman, Sp.Rad(K)

Departemen Radiologi Fakultas Kedokteran UNPAD-RSHS. Bandung
Jl. Pasteur no.38. Bandung
40161

Abstract

Background
Transarterial Chemoembolization (TACE) combines transarterial delivery of chemotherapeutic agents to the tumor bed, which is followed by embolization of the tumor vascularity. Transcatheter arterial chemoembolization (TACE) has been recognized as an effective palliative treatment option for patients with advance HCC.
Hepatocellular carcinoma (HCC) is the fifth most common cancer that predominantly occurs in liver cirrhosis of patients. It requires staging systems to design the treatments. The Barcelona Clinic Liver Cancer (BCLC) staging system is the most common guideline, which is used for HCC management. For Barcelona Chlinic Liver Cancer (BCLC) stage B (intermediate HCC), Transarterial Chemoembolization (TACE) is the standard treatment. TACE is shown to improve median survival from 16 to 20 months.
Objective
This study assesses the effectiveness of Transarterial Chemoembolization (TACE) in hepatocellular carcinoma cases.
Method
Transarterial Chemoembolization (TACE) for Hepatocellular Carcinoma
Result
A patient, 66-year-old male, visited Hasan Sadikin Hospital (RSHS) Bandung to undergo TACE.The patients complaints were severe nausea and the feeling of being tired quickly since the last 3 months. The patient had a history of Hepatitis B 10 years ago.
The examination was continued with ultrasonography (USG) and the result showed a lesion in the right lobe of the liver. After that, the medical imaging was enhanced by performing a computed tomography scan (CT scan) and a 6,4 x 5,09 x 4,1 cm inhomogeneous isodense lesion was found in the 4th segment of the right liver, which was supporting a hepatocellular carcinoma. The HCC was classified according to the BCLC and Child-Pugh criteria as hepatocellular carcinoma stage B Child-Pugh A.
Furthermore, the patient was treated with TACE at the RSHS Bandung Hospital.
Conclusion
There was a decrease in the size of the mass, shows the success TACE.

Keywords: Transarterial Chemoembolization

Topic: Biomedical Science