Effectivity of Ethanol Extract of Babadotan leaves (Ageratum conyzoides) Against Musca domestica
Lutfhi Nurlaela, dr., M.Kes (a), Ali Taufan, dr., MH.Kes (b), Ranti Zalfa Husniyyah Utami (a)

(a) Laboratory of Parasitology, Faculty of Medicine, Jenderal Achmad Yani University, Cimahi

(b)Forensic and Medicolegal Laboratory, Faculty of Medicine, Jenderal Achmad Yani University, Cimahi

Abstract

The house fly, Musca domestica (M. domestica), is the largest synanthropic insect found in poor sanitation. House flies act as mechanical vectors that transmit pathogenic agents, so that an excessive increase in fly populations can cause health problems for humans. The use of synthetic chemical compounds is still the main choice in controlling the population of M. domestica, but it can trigger resistance to insects, disrupt human health, and pollute the environment. To avoid these bad effects, it can be done by developing the use of natural insecticides. One plant that has the potential to be a natural insecticide is Ageratum conyzoides (A. conyzoides) which is known as the babadotan plant. Babadotan plants contain bioactive compounds that can interfere with larval growth and development. The purpose of this study was to determine the effectiveness of the ethanol extract of babadotan leaves as a larvicide against M. domestica. This research is an experimental study with a Posttest Only Control Group Design. The ethanol extract of babadotan leaves was made in several concentrations, namely 10%, 30%, 50%, 70%, and 100% then dropped directly on the third instar larvae of M. domestica. The research data were analyzed using the One-Way ANOVA test and probit analysis. The results showed that the 10% concentration could kill 43% of larvae and the mortality rate continued to increase until it reached 97% at 100% concentration so that all concentrations of babadotan leaf ethanol extract (Ageratum conyzoides) had a larvicidal effect on instar III larvae of Musca domestica. The Lethal Concentration (LC90) value of the ethanol extract of babadotan leaves was at a concentration of 48.123%. This is due to the active compounds contained in the ethanol extract of babadotan leaves such as alkaloids, flavonoids, saponins, and steroids/triterpenoids

Keywords: Ageratum conyzoides, Larvacides, LC90, Musca domestica

Topic: Biomedical Science