NEUROCOGNITIVE COMPLICATIONS IN COVID 19
Yustiani Dikot

Department of Neurology, Medical Faculty, Universitas Jenderal Achmad Yani

Abstract

Corona virus Disease 2019 (COVID-19) has emerged in Wuhan, China the outbreak of this infection was declared as pandemic a global public health emergency by WHO in March 2020. Respiratory viruses that infect the upper respiratory tract in humans and cause highly acute lethal pneumonia with clinical similarities to those reported in SARS-Co V and MERS-Co V including neurological manifestation. Some viruses have neuro invasive properties and activate the immune response in the brain. These immune events may be neuroprotective or they may cause long-term damage similar to what is seen in some neurodegenerative diseases. WHO declared epidemiological and clinical features of COVID-19 patients are currently well characterized also for neurological sign and symptoms, most of SARS patients had the common complaints, such as anosmia, dysgeusia, headache, poor concentration, declined memory, and insomnia, as well as , anxiety and depression symptoms, indicating cognitive impairments after SARS infection. Other neurological manifestation caused by COVID-19 patients including encephalopathy, encephalitis and cerebrovascular pathologies, acute myelitis, and Guillain-Barre syndrome, this neurological impairment cause by neurological involvement or as a complication of other organ impairment

Keywords: COVID-19, Respiratory viral infection, Neuroinvasion, Acute and chronic neurocognitive complication

Topic: Clinical Practice in Pandemic Era