The Correlation between thrombocyte count and type of Plasmodium sp with degree of malaria infection and thrombocyte count with type of Plasmodium sp in malaria patient
Susanti Ratunanda1, Eddy Harjadi S3, Eka Ulfah R2

1)Clinical Pathology Department 2)Internal Medicine Department 3)Faculty of Medicine
Faculty of Medicine - Universitas Jenderal Achmad Yani

Abstract

Malaria is one of life-threatening infectious diseases in Indonesia especially in high risks group that caused by Plasmodium sp. Malaria is classified into uncomplicated malaria and severe malaria degrees. Thrombocytopenia is one of common result from thrombocyte count examination that can be related to hemorrhagic risks in malaria patients. The purpose of this study was to determine the correlation between thrombocyte count and type of Plasmodium sp. with degree of malaria, and thrombocyte count with type of Plasmodium sp. in malaria inpatient at Dustira Hospital Cimahi. Analytical method was used in this study with cross sectional design. This study was conducted in patient who has diagnosed with malaria with or without complication, has result of thrombocyte count examination and type of Plasmodium sp. with no co-infection in the same period of illness. Data were taken from medical record and clinical laboratory department of Dustira Hospital in the period of 2014-2017. There were 59 malaria patients who met the inclusion criteria. This study showed that most malaria patient were in age groups 26-45 years old (62.7%) and mostly male (96.6%). A total of 46 malaria patients (78%) had thrombocytopenia with an average thrombocyte count of 110,000 mm/m3. The majority of Plasmodium sp. that caused malaria infection was P. vivax (72.9%) followed by P. falciparum (25.4%) and mixed malaria (1.7%). There is no significant correlation between thrombocyte count with degree of malaria patient (p=0,537, R=0,082), significant correlation between type of Plasmodium sp. with degree of malaria patients (p=0.03, R=0,375) and no significant correlation between thrombocyte count with the type of Plasmodium sp. (p=0.133, R=0.198). The correlation between thrombocyte count with degree of malaria and type of Plasmodium sp. results in this study can be caused due to the unknown data of thrombocyte count baseline and history of previous malaria treatment of the patient.

Keywords: degree of malaria, thrombocyte count, type of Plasmodium sp

Topic: Clinical Practice in Pandemic Era