The Effect of Heart Infarction on Electrocardiogram value of Porcine (Sus scrofa) as a Model for Human
Gunanti (a,1), Normalina Sandora (b,2) , Muhammad Arza Putra (c), Nur Amalina Fitria (b), Tyas Rahmah Kusuma (b), Melpa Susanti Purba (a), Arief Boediono (a) , Deni Noviana (a,d*)

a) Faculty of Veterinary Medicine (FKH), IPB University, Bogor, 16680, Indonesia
b)Human Reproduction, Infertility and Family Planning, Indonesia Medical Education and Research Institute (IMERI), Jakarta, 10430, Indonesia
c)Department of Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta Pusat, 10430, Indonesia
d)The Veterinary Medical Teaching Hospital (RSHP), IPB University, Bogor, 16680, Indonesia
1) First author
2) Co-author
*Corresponding Author: deni[at]apps.ipb.ac.id

Abstract

Cardiovascular disease is the most cause of death, whilst one out of four dead in Indonesia was related to coronary heart disease, consuming health budget up to US-943 million in 2016. The obstruction of a coronary artery causes myocardial infarction. Electrocardiography (ECG) is a routine device to indicate electrical conduction of the heart. This study aims to evaluate the value of ECG after infarction of the heart. Elektrocardiography was performed before the induction of cardiac infarction as a normal result. The anesthesized porcine placed in right lateral recumbency. The table was insulated from metal surface using underpad. Five ECG electrodes placed on the 2 forelimbs, the 2 hindlimbs, and the sternum. The hair in those areas clipped beforehand. The tape and additional gel were used to improve contact between the patient and electrodes. The electrodes were connected to the ECG machine by color-coded cables. The occlusion performed in this study was at the 1 per 3 distal of the left anterior descendant (LAD). After 60 minutes surgery, the ECG was performed again as immediately 60 min after induction. After a month, we ECG wak taken again to see the value of application infarct in porcine. The T amplitude and ST wave 60 minutes after treatment was elevated. After first month observation, the ST elevation had disappeared and abnormal Q waves were found. Elektrocardiography of porcine after 60 minutes induction showed a typical myocardial infarct (MCI) and after a month showed the indication of myocardial hypoxia and myocardial infarction.

Keywords: Electrocardiography, porcine myocardial infarction, left anterior descendant, ST elevation

Topic: Animal Science