Association of thyroid hormone with nutritional status, triglyceride serum and blood pressure in patient with goiter in clinic of Magelang Health Research and Development Center Yusi Dwi Nurcahyani (a*), Suryati Kumorowulan (a), Prihatin Broto Sukandar (a), Cati Martiyana (a)
Balai Litbangkes Magelang
Abstract
Thyroid hormones affect lipid and glucose metabolism, blood pressure,and body weight, all of which are associated with various metabolic parameters- abnormal thyroid function may hence result in the development of metabolic syndrome. The aim of the present study is to evaluate the association of thyroid dysfunction with MetS and its components. Cross-sectional study of 83 participants who met the inclusion and exclusion criteria. Total cholesterol, LDL, HDL, TSH and free T4 concentration were measured in all subjects. BMI and blood pressure were measured. Concentrations of lipids and lipoproteins, free T4 and TSH were assayed. Mean age of the participants was 33.5 +- 8.6 of whom 6 (7.2 percent) subclinical hypothyroidism, 17 (20.5 percent) overt hyperthyroidism, and 17 (20.5 percent) had subclinical hyperthyroidism. Linear regression analysis showed positive associations for TSH with systolic, in addition FT4 was associated with BMI, systole and diastole after adjustment for age. Overt hyperthyroidism had significantly higher odds of hypertension after full adjustment for age and BMI (OR 5.557 (1.310-23.578), p<0.05). Hyperthyroidism may induce hypertension.
