What is the Profile of Quality of Life for Controlled Patients Taking Antiretrovirals? An Observation in Indonesia
Setiyo Budi Santoso (a*), Heni Lutfiyati (a), Ulfahishofi Hanifah Afifi (b), Shellyta Ratnafuri (b)

a) Department of Community and Clinical Pharmacy, Faculty of Health Science, Universitas Muhammadiyah Magelang
b) KRT Setjonegoro Regional Public Hospital, Wonosobo, Indonesia

Abstract

Number of those who have been affected by HIV and AIDS in Indonesia is around 242,699 and 87,453. The government provides antiretroviral therapy to reduce the spread of infections and mortality. Depression, stigma, the length period of therapy and suffering become factors reducing quality of life. Meanwhile, high CD4 values, educational background, social and spiritual support can improve the quality of life. The results of this study present a quality of life profile for PLHIV based on differences in antiretroviral therapy regimens. This research is an observational study. Data was collected by cross sectional method. The study involved as many as 66 HIV patients undergoing controlled therapy at KRT Setjonegoro Wonosobo Hospital. The instrument used was the WHOQOL HIV BREF indonesian version consisting of 6 domains. The average value of quality of life of PLHIV are physical domain (15.15), psychological domain (14.72), independence domain (15.20), social domain (15.45), environmental domain (14.43) and spiritual domain (15.27). Based on antiretroviral therapy regimens of quality of life with above average values found in PLWHA who underwent ZDV-3TC-NVP (3 domain), ZDV-3TC-EFZ (1 domain), ZDV-3TC-LPV (2 domain), TDF- 3TC-NVP (5 domains), TDF-3TC-EFZ (1 domain), TDF-FTC-NVP (5 domains) and TDF-FTC-EFZ (1 domain).

Keywords: Antiretroviral Therapy, WHOQOL HIV-BREF, Indonesia

Topic: Medicine and Health Sciences